PLASMID PROFILING OF EXTENDED SPECTRUM Β-LACTAMASES PRODUCING ESCHERICHIA COLI IN SOME HOSPITALS IN BAGHDAD

This study was aimed to determine the prevalence of ESBLs in E. coli and their relation plasmid profiling patterns a sample patients Iraqi hospitals. The total number isolates 91 (49%) were collected out 185 clinical samples. antibiotic sensitivity test for showed high resistance percentage Nitrofurantion 95.7%, amoxicillin Ceftriaxone each which 91.3% Ceftazidime 90.2%, while highest observed against Imipenem 100%, Meropenem 99% then Amikacin 93.5%. Multi drug resistant (MDR) 53(58.2) % producers 45 (49.5) %. Plasmid profile analysis nineteen different obtained based on molecular weight plasmids content. Most β-lactamase had multiple plasmids, where’s single predominant non-β-lactamase-producing isolates. presence common among increases distribution community. In conclusion, producing bacteria can transferred between species by leading cross give limited options treatment.